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Streptococcus pneumoniae by Mind Map: Streptococcus
pneumoniae
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Streptococcus pneumoniae

Carriage

High Carriage

Higher Replacement Potential

Disease

Vaccination

Polysaccharide vaccine

not efficient in young children, immunitary system immaturity?

Conjugate vaccine

19A pos-appocalyptic (PCV7) main cause of IPD

Included serotypes, (4, 6B, 9V, 14, 18C, 19F, and 23F)

vaccine-related serotypes, vaccine-related serotypes, 6A, 9A,L,N, 18A,B,F, 19A,B,C, 23A,B

Imunity

Competition between 2 serotypes

Acquired immunity

serotype-specific

Antibody-dependent

T-cell-dependent, Antibody-independent

vaccination-dep

2008 - Pneumococcal vaccines: mechanism of action, impact on epidemiology and adaption of the species  

Polysaccharide vaccine, Bcell-dependent reaction, protects against bacteraemia, does not protect against pneumococcal infection (colonization)

indirect effect, associated serotypes

Staphilococcus aureus

2008 - Does pneumococcal conjugate vaccine influence Staphylococcus aureus carriage in children?

pilus?

2009 - The pneumococcal pilus predicts the absence of Staphylococcus aureus co-colonization in pneumococcal carriers.

Recombination

capsular switching after vaccination!

2008 - Pneumococcal vaccines: mechanism of action, impact on epidemiology and adaption of the species