Online Mind Mapping and Brainstorming

Create your own awesome maps

Online Mind Mapping and Brainstorming

Even on the go

with our free apps for iPhone, iPad and Android

Get Started

Already have an account? Log In

Classification of Hypersensitivity Reactions by Mind Map: Classification of Hypersensitivity
Reactions
0.0 stars - 0 reviews range from 0 to 5

Classification of Hypersensitivity Reactions

Type I

Immediate hypersensitivity

IgE mediated response

Release of mediators result in:

vasodilation

Increased capillary permeability

Mucus hypersecretion

Smooth muscle spasm

Tissue infiltration with eosinophils, TH2, and other inflammatory cells

Example

Atopic diorders, Allergig Asthma, Allergic rhinitis, Allergic conjuctivitis

Anaphylaxis

Developed in < 1hr after exposure to antigen

Type II

antibody-dependent cytotoxic hypersensitivity

The antigen-antibody complex activates cells that participate in antibody-dependent cell-mediated cytotoxicity, complement, or both.

It results in cell and tissue damage

Examples:

Hyperacute graft rejection of an organ/graft transplant

Coombs-positive hemolytic anemia

Hashimoto thyroiditis

Anti-glomerular basement membrane disease

Type IV

Delayed hypersensitivity

T-cell mediated

T-cells are activated by re-exposure to antigen

Tissue damage through direct toxic effect or through the release of cytokines

Examples:

Contact dermatitis

Allograft rejection

Hypersensitivity peneumonitis

Immune response to TB

Some forms of drug hypersensitivity

Type III

Immune complex disease

Antigen-antibody reaction

causes systemic immune response

Examples

Serum sickness

Systemic Lupus Erythematosus (SLE)

Rheumatoid arthritis

Leukocytoclastic vasculitis

Hypersensitivity penumonitis

Develops 4-10 days after exposure to antigen. If exposure to the antigen continues, can become chronic

Resources

Here

Here

Here

--