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Recanalization and clinical outcome after intravenous thrombolysis of basilar occlusion as a function of onset to treatment time (OTT) by Mind Map: Recanalization and clinical outcome after intravenous
thrombolysis of basilar occlusion as a function of onset to
treatment time (OTT)
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Recanalization and clinical outcome after intravenous thrombolysis of basilar occlusion as a function of onset to treatment time (OTT)

Author: Lindsberg

Background

Basilar artery occlusion (BAO) is devastating with high mortality 85-95%

RCT's have not been performed

Recanalization therapy

iv / ia thrombolysis?

Mechanical thrombectomy?

Combination?

Lindsberg & Mattle, Stroke 2006

IVT or IAT thrombolysis?

BASICS-registry, Schonewille WJ et al, Lancet Neurology 2009

Time window?

no recommandations yet

Helsinki 1995-2010

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Clinical phenotypes

Sudden onset with severe symptoms

Sudden onset with prodromal symptoms

Progressive/waxing and waning symptoms

Vascular diagnosis essential (CT-angio, MRA,DSA)

necessary for thrombolysis

Predictors of outcome

Outcome(s)

mRS

Results

Recanalization in 65%, subgroup with repeat angiographs

Outcome at 3 months, Untitled, predictors of good outcome, predictor of poor outcome, very poor outcome, Death

OTT and very poor outcome

Outcome in coma with BAO picture

Conclusions

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