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Leukemia by Mind Map: Leukemia

1. Acute

1.1. Fatigue, bleeding infections

1.1.1. BM Smear: > 20% Blasts

1.2. ALL

1.2.1. kids

1.2.2. Infiltrate: CNS and testes

1.2.2.1. intrathecal MTX

1.2.3. t(12:21)

1.2.4. Rx

1.2.4.1. Fluids

1.2.4.2. Allopurinol, Rasburicase

1.3. AML

1.3.1. Smear: Auer Rods

1.3.2. AML M3(t 15:17)

1.3.2.1. risk DIC

1.3.2.2. Rx: ATRA

1.3.3. Rx: Idarubicin + cytosine arabinoside

2. Chronic

2.1. CML

2.1.1. young

2.1.1.1. if untreated - Acute

2.1.1.1.1. Risk stroke, priapism

2.1.1.2. Dx

2.1.1.2.1. - LAP

2.1.1.2.2. PCR DNA

2.1.1.2.3. FISH

2.1.1.3. Rx

2.1.1.3.1. Imatinib

2.1.1.3.2. BM transplant

2.2. CLL

2.2.1. Old

2.2.1.1. Dx

2.2.1.1.1. Smear: Smudge cells

2.2.1.2. Stages

2.2.1.2.1. Stage 0

2.2.1.2.2. Stage

2.2.1.2.3. Stage

2.2.1.2.4. Stage

2.2.1.2.5. Stage

2.2.1.3. Richter's transformation

2.2.1.3.1. NHL