Contact Dermatitis

1. Treatment

1.1. Avoidance of offending agents

1.2. cool compress

1.3. sedating antihistamines

1.4. topical aluminum sulfate calcium actate

1.5. antibiotics

1.6. anti-inflammatory agents

2. Diagnosis

2.1. patch testing

2.2. Repeat open application test

2.3. Potassium hydroxide preparation and/or fungal culture

2.4. Skin biopsy

2.5. Dimethylgloxime test

3. Adaptive Response

3.1. Sensitization

3.1.1. haptens combine epidermal protein

3.1.2. forms memory Tcells formed

3.1.3. takes 10-14 days

3.2. Elicitation

3.2.1. occurs after re-exposure

3.2.2. local inflammatory response

3.2.3. anamnesis

3.2.3.1. pruritic rash

3.2.3.2. erythmatous

3.2.3.3. papula

4. Clinical Presentation

4.1. Mild Irritants

4.1.1. erytgena

4.1.2. chapped skin

4.1.3. dryness

4.1.4. pruritis

4.2. Severe Irritants

4.2.1. edema

4.2.2. serous oozing

4.2.3. extreme tenderness