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Genome sequencing by Mind Map: Genome sequencing
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Genome sequencing

applications

somatic sequencing

"counting methods"

exome sequencing

de novo assembly

re-sequencing

history

progress as

techniques

generation

in detail

resources

videos

initiatives

definition

whole-genome sequencing

pair-end

Paired-end reads Reads that are sequenced from both ends of the same DNA fragment. These can be produced by a variety of sequencing protocols, and paired-end preparation is specific to a given sequencing technology. Some recent sequencing vendors use the terms ‘paired end’ and ‘mate pair’ to refer to different protocols, but these terms are generally synonymous.

Multi-reads

A DNA sequence fragment (a ‘read’) that aligns to multiple positions in the reference genome and, consequently, creates ambiguity as to which location was the true source of the read

Copy number variation

single nucleotide polymorphism

missing terms

Challenges

repetitive DNA

Computational analysis

existing tools

workflow

Genome annotation

identifying elements/structure in genome

Attaching biological information to these

Structural annotation

Functional annotation