Why is it not happening yet?
from bone marrow
Aims, cell replacement, cell restoration, neurogenesis
How to use?, isolate mesenchymal cells, differentiate to dopamin producing neurons, convert to astrocytes, This was done, cells express astrocyte biomarkers, produce GDNF and BDNF, prevent further dopaminergic neuronal degeneration, slow down disease progression, induce axonal sprouting from surviving, Graft, transplant fully differentiated cells
Biomedical start up company, Petah Tikvah, autologous stemcell transplantation, safety data is gathered for ALS