Symptoms

1. Slowed growth

2. Seizures

3. Cognitive delay

4. Walking on toes

5. Sleep problems

6. Skin breakdown caused by hands in mouth

7. Teeth grinding

8. Loss of motor function

9. Apraxia; inability to perform a task despite willingness to

10. Hand wringing

11. Feeding difficulty like chewing

12. Breathing difficulty

13. Inability to verbally communicate