Immunity Response

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Immunity Response by Mind Map: Immunity Response

1. Specific

2. Cell-Mediated Immunity

2.1. Role player:T lymphocyte-Produce in bone marrow mature at thymus

2.2. T lymphocyte is activated after binding to antigen on APC, sensitised , enlarge and divide

2.3. Form Clone - Helper T Cell, Suppressor T cell, Killer T cell and memory T-cell

2.4. Helper T- secrete cytokines (Interleukin 2)~Stimulate maturation of B cells, activate more lymphocyte at site of infection, attract macrophage , enhance phagocytic action

2.5. Killer T cell-secrete granzyme and perforin -causes cells undergo suicide(Apoptosis)

2.6. Suppressor T cell- inhibit B and T cells after the all the pathogen is killed or to control the activity of B and T cells

2.7. Memory T cell-Responsible for secondary response making body able to react faster if the same pathogen invade the body again

3. Antibody Mediated Immunity

3.1. Role Player-B cells~Produce and mature at bone marrow

3.2. B cells is activated after binding to antigen,sensitised , enlarge and divide

3.3. Form clone-Plasma cells and memory B cells

3.4. Plasma Cell- Secrete antibody into bloodstream

3.4.1. Antibody can:

3.4.2. Combine with foreign bacteria toxin, inactivate them by inhibiting reaction with other cell(Neutralisation )

3.4.3. Bind to surface-prevent antigen from entering the cell(Neutralisation )

3.4.4. Coat the pathogen-easier for phagocyte to engulf and digest(Opsonisation )

3.4.5. Clump antigen together (Agglutination)

3.4.6. Dissolve pathogen

3.4.7. Making soluble pathogen to insoluble ( Precipitation )

3.5. Memory B cell- Enable body to make more antibody at a faster rate if the same antigen invade body again

4. Non Specific

5. External Defence

5.1. Hair , Cilia, Mucus membrane, Flushing action , Cerumen, Skin, Lysozyme, Acids

6. Protective Reflex

6.1. Sneezing, Coughing, Diarrhoea,Vommiting

7. Internal Non Specific Reflex

7.1. Phagocyes

7.1.1. Macrophage and Neutrophil-engulf and digest antigen - Not discriminate

7.2. Inflammation

7.2.1. Reddish,Warm-Vasodilation of blood vessel as a result of histamine, Pain-Pain receptor stimulated, Swelling-Plasma inside the blood flow out

7.3. Fever

7.3.1. Because of lymphocyte secreting Pyrogene -Body thermostat set body temperature at higher level - not suitable for pathogen and increase rate of reaction of macrophage