Online Mind Mapping and Brainstorming

Create your own awesome maps

Online Mind Mapping and Brainstorming

Even on the go

with our free apps for iPhone, iPad and Android

Get Started

Already have an account? Log In

Photodynamic Therapy by Mind Map: Photodynamic Therapy
0.0 stars - reviews range from 0 to 5

Photodynamic Therapy

Mechanism of Action

Exogenous ALA Applicaion

Incubation (Metabolism & Accumulation)

  Definition: Time between drug application and light treatment Porphyrin precursors require an incubation period for metabolism    

Light Exposure


Metabolism and Re-accumulation of Porphyrins


ALA itself is not a photosensitizer

Accumulation of Protoporphyrin IX depends on?

Peripheral Benzodiazapine Receptors are overexpressed in cancers

PBRs are overexpressed in  neoplastic cells, enhancing  ALA-PDT efficacy in cancer  treatment

Light Sources

Porphyrin Absorption Spectrum (300-650 nm)


FDA Approved



Photosensitivity at 400-450 nm


Allergies to Porphyrins

Adverse Effects

Phototoxic Reaction


HSV (Prophylaxis prior Tx)

Residual photosensitivity