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Anemia by Mind Map: Anemia

1. RE Phagocytosis

1.1. Autoimmune

1.2. Heinz body anemia

1.3. Membrane -ATP

2. Hypoproliferative (Proliferation defect)

2.1. Low erythropoietin

2.1.1. Increase O2 release

2.1.2. Renal disease

2.1.3. Reduced O2 requirement

2.2. Lack of Iron

2.2.1. Inflammation

2.2.2. Chronic bleeding

2.2.3. Iron deficiency

2.3. Bone marrow damage

2.3.1. External toxin - aplastic

2.3.2. Myelopthisic

2.3.2.1. fibrosis of bone marrow

2.3.3. Intrinsic marrow disease

2.3.3.1. autoimmune

3. Ineffective (maturation deffect)

3.1. Macrocytic

3.1.1. Reticulocyte proliferation index check

3.1.1.1. RPI >2

3.1.1.1.1. Survival defect

3.1.1.2. RPI < 2

3.1.1.2.1. Megaloblastic (nuclear maturation defect

3.1.1.3. RPI < 2

3.1.1.3.1. Non megaloblatic

3.2. Normocytic

3.2.1. Normochromic

3.2.1.1. RPI >2

3.2.1.1.1. Survival defect

3.2.1.2. RPI < 2

3.2.1.2.1. Proliferation defect

3.3. Microcytic

3.3.1. Hypochromic

3.3.1.1. serum iron

3.3.1.1.1. decresead

3.3.1.1.2. Normal / increased

4. Hemolytic (survival defect)

4.1. Fragmentation

4.1.1. intravascular clotting

4.1.2. Vasculitis

4.1.3. Sickle cell anemia

4.2. Intravascular hemolysis

4.2.1. C perfringens exotoxic

4.2.2. Complement - autoimmune

4.2.3. G6PD and Drugs, Favism

4.2.4. Water, Heat